For the next two weeks, we’re presenting some of our favorite TEDTalks from among the 270+ talks and performances we’ve posted since June 2006. Look for brand-new TEDTalks starting August 18. Until then, enjoy these gems — and suggest your own by writing to firstname.lastname@example.org or joining the conversation on TED.com. In the TED tradition […]Continue reading
Why you should listen
Peter Donnelly applies statistical methods to real-world problems, ranging from DNA analysis (for criminal trials), to the treatment of genetic disorders. A mathematician who collaborates with biologists, he specializes in applying probability and statistics to the field of genetics, in hopes of shedding light on evolutionary history and the structure of the human genome.
The Australian-born, Oxford-based mathematician is best known for his work in molecular evolution (tracing the roots of human existence to their earliest origins using the mutation rates of mitochondrial DNA). He studies genetic distributions in living populations to trace human evolutionary history -- an approach that informs research in evolutionary biology, as well as medical treatment for genetic disorders. Donnelly is a key player in the International HapMap Project, an ongoing international effort to model human genetic variation and pinpoint the genes responsible for specific aspects of health and disease; its implications for disease prevention and treatment are vast.
He's also a leading expert on DNA analysis and the use of forensic science in criminal trials; he's an outspoken advocate for bringing sensible statistical analysis into the courtroom. Donnelly leads Oxford University's Mathematical Genetics Group, which conducts research in genetic modeling, human evolutionary history, and forensic DNA profiling. He is also serves as Director of the Wellcome Trust Centre for Human Genetics at Oxford University, which explores the genetic relationships to disease and illness.
What others say
“Donnelly is at the forefront of looking at the variation of genes within the human species to try and find out what is really relevant to disease. He has developed a fundamental framework for analyzing genome data that is leading to conclusions about human evolution, and even early human history.” — Scientific Computing World