What is Merrem?Merrem is an antibiotic used to treat certain bacterial infections of the skin or abdomen; or central nervous system (CNS) infections in children. Merrem may also be used to treat other bacterial infections, as determined by your doctor. Merrem is administered intravenously (through a vein in your arm).
What is the most important information I should know about Merrem?Your doctor will not administer Merrem if you are allergic to it, any of its ingredients, or similar antibiotics (such as penicillin, cefazolin, or cefepime). If you are allergic to similar antibiotics, it is possible for you to have an allergic reaction to this medication. Tell your doctor or seek medical attention immediately if you take Merrem and feel signs of an allergic reaction (such as a rash or difficulty breathing).
Seizures or other central nervous system (CNS) disorders have been seen with the use of Merrem, especially if you have a history of seizures, other CNS disorders, or kidney problems. Also, Merrem can decrease the effects of certain seizure medications (such as divalproex sodium or valproic acid).
Merrem can cause diarrhea or colitis (inflammation of the colon). This can occur a couple of months after taking the last dose of Merrem. Tell your doctor immediately if you have diarrhea or colitis.
Who should not take Merrem?Your doctor will not administer Merrem to you if you are allergic to it, any of its ingredients, or any similar antibiotics (such as cefazolin, or cefepime, or penicillin).
Your doctor will not administer Merrem to treat viral infections, such as the common cold or flu.
What should I tell my doctor before I take the first dose of Merrem?Tell your doctor about all prescription, over-the-counter, and herbal medications you are taking before beginning treatment with Merrem. Also, talk to your doctor about your complete medical history, especially if you have allergies, history of seizures, other CNS disorders, kidney disease, are pregnant, plan to become pregnant, or are breastfeeding.
What is the usual dosage?The information below is based on the dosage guidelines your doctor uses. Depending on your condition and medical history, your doctor may prescribe a different regimen. Do not change the dosage or stop taking your medication without your doctor's approval.
Adults: The recommended dose is 500-1000 milligrams (mg) every 8 hours. Your doctor will administer the appropriate dose for you based on the type and severity of your infection.
If you have kidney impairment, your doctor will adjust your dose appropriately.
Children ≥3 months: Your doctor will prescribe the appropriate dose for your child, based on their weight or the type and severity of their infection.
How should I take Merrem?Your doctor will administer Merrem to you.
What should I avoid while taking Merrem?Do not miss your scheduled follow-up appointments with your doctor.
What are possible food and drug interactions associated with Merrem?If Merrem is used with certain other drugs, the effects of either could be increased, decreased, or altered. It is especially important to tell your doctor if you are taking any of the following prior treatment with Merrem: divalproex sodium, probenecid, or valproic acid.
What are the possible side effects of Merrem?Side effects cannot be anticipated. If any develop or change in intensity, tell your doctor as soon as possible. Only your doctor can determine if it is safe for you to continue taking this drug.
Side effects may include: abdominal pain, allergic reactions, breathing problems, chills, confusion, constipation, dehydration, diarrhea, dizziness, fever, headache, injection-site inflammation, irregular heartbeat, itchiness, nausea, nervousness, rash, seizures, vomiting, weakness, weight loss
Can I receive Merrem if I am pregnant or breastfeeding?The effects of Merrem during pregnancy and breastfeeding are unknown. Tell your doctor immediately if you are pregnant, plan to become pregnant, or are breastfeeding.
What should I do if I miss a dose of Merrem?Merrem should be given under special circumstances determined by your doctor.
How should I store Merrem?Your doctor will store this medication for you.