The goal of the present study was to characterize high school students’ (n = 338) exposure to geospatial technologies and investigate factors predicting enrollment in a GIS course. Students who reported using GIS were almost 10 times more likely to enroll than students without experience using GIS. Males were more than 3 times more likely to enroll than females. Spatial skills, but not beliefs about spatial ability, also predicted enrollment. These results underscore the importance of providing opportunities for students to use geospatial technologies as a pathway to students’ future learning and training for GIS related careers.