UF scientists program blood stem cells to become vision cells
...ose to build retinal pigment epithelial cells, which form the outer barrier of the retina. In addition to being very specialized and easy to identify, rpe
cells are faulty in many retinal diseases, including age-related macular degeneration, which affects nearly 2 million people in the United States, and...
Stemedica Discovers Significant Breakthrough in the Use of Stem Cells and Stem Cell Factors for the Treatment of Retinal Degeneration
...s, "There were two very encouraging findings: rpe
stem cells injected into the suprachoroidal space prevented the animal's rpe
cell's degeneration as well as preventing degenera...of degeneration in the fellow eye. Degeneration of rpe
cells occur in many other human retinal diseases s...
LSUHSC research identifies enzyme that makes survival molecule for key vision cells
... the survival of rod and cone photoreceptor cells. rpe
cells regulate the renewal of the tips of photoreceptor cells among other functions. When rpe
cells do not function properly, photoreceptor cell...mber of stressors, including free radicals, damage rpe
cells. Dr. Bazan's lab has shown that...
'Dark cells' of living retina imaged for the first time
... The cells, called retinal pigment epithelial, or rpe
cells, are nearly black, and form a layer that rec... shuttled out of the photoreceptor and down to the rpe
cells. The rpe
cells recharge the photopigment molecules and send...
Ellex Announces New Retina Regeneration Therapy to be Presented at the AAO
... preserve vision. Laboratory research conducted under
Professor Marshall over the past few years has demonstrated that the Ellex
2RT method causes the rpe
to migrate and release matrix metalloproteinase
(MMP's), which are the enzymes that clean up Bruch's membrane. Further
laboratory experiments to measu...
Stem Cell Therapy Could Provide Cure for AMD in Five Years
...ls, which are effective in replacing dysfunctional rpe
and photoreceptors found in AMD, leading to a surg... cells in Sheffield, confirming that the cells are rpe
cells and preparing them in a form for transplant ...ction based on studies on transplanting autologous rpe
(i.e. cells from the patients' own eyes) at Moorfi...
Biologists Trace Cause Of Early Blindness To Tissue Defect
.... Their results suggest therapies that correct the rpe
may successfully rescue photoreceptor loss in chor...eceptors was perfectly normal, but the neighboring rpe
was defective, which is why the photoreceptors wer...nctional gene can potentially be added back to the rpe
using gene therapy.”
In addition to being ...
Cell transplantation - Potential treatment for blindness
...was cultured from human embryonic stem cell lines. rpe
are the cells that support the light sensing cells in the eye. The cultured rpe
was then transplanted into the eyes of a special breed of rat that had an rpe
defect, resulting in blindness. It was found that ...
Another feather in fish oil cap: hope against retinal degenerative diseases
... acid signaling, neuroprotection and photoreceptors.'
Dr. Bazan's LSUHSC group, in collaboration with Harvard, has revealed the importance of DHA. rpe
cells cope with sunlight and oxidative stress, as well as trauma, by using antioxidants like Vitamin E, present in the cells. Dr. Bazan and colleagues...
Blindness can be stopped with drug for acne treatment
...-pigmented epithelium (RPE), a layer of cells near the retina. The accumulation of toxic pigments, or lipofuscin// results in the deterioration of the rpe
leading to loss of rods and cones and subsequent central vision loss.
Researchers from the University of California, Los Angeles, have now found ...