Energy, Enzymes, and Catalysis Problem Set
Problem 5: Why do enzymes reach a maximum rate at high substrate concentration?
In the presence of alcohol dehydrogenase, the rate of reduction of acetaldehyde to ethanol increases as you increase the concentration of acetaldehyde. Eventually the rate of the reaction reaches a maximum, where further increases in the concentration of acetaldehyde have no effect. Why?
Department of Biochemistry and Molecular Biophysics
University of Arizona
Wednesday, September 25, 1996
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