Aptamers are short RNA or single-stranded DNA molecules that can fold into unique three-dimensional conformations. Then aptamers bind to their targets (e.g. specific type of cells or proteins) with high binding specificity and affinity. Therefore, they are promising agents in both diagnostic and therapeutic applications.
The imbalance between bone formation and bone resorption will lead to different diseases, such as Osteoporosis, Osteogenesis imperfecta (OI, a.k.a. “brittle bone disease”). A new class of aptamer has been developed to promote bone formation, and thus it’s a potential agent for treating OI. Also, those highly specific aptamers can be further developed for targeted drug delivery for treating cancers.
Aspiring to be a leading, research-led, liberal arts University in Asia, Hong Kong Baptist University is committed to conducting world-leading investigations that extends the frontiers of knowledge, tackles global challenges and benefits the community at home and abroad.
Pursuing research excellence is one of the priorities of the University’s Institutional Strategic Plan 2018-2028. The University keeps enhancing its capacity and strength to produce world-class research with an aim to bring significant impact to the society.