Genital herpes is a common sexually transmitted infection caused by the herpes simplex virus (HSV). This article discusses an overview of HSV, diagnosis and workup, as well as treatment options for management of genital herpes.
Recurrent herpes labialis is a common condition associated with the formation of vesicles around the mouth, often preceded by prodromal symptoms including tingling and burning. The purpose of this article is to serve as a practical guide in the management of recurrent herpes labialis by summarizing current treatments and discussing potential new therapies.
Over all, acyclovir is a safe and effective drug with rare side effects when used as short term treatment. There are some concerns about side effects when acyclovir is used as long term suppressive therapy in patients, particularly pertaining to the kidneys and the blood system.
For the treatment of labial herpes, a single 1,500mg dose of famciclovir shortened the lesion healing time, shortened the time to normal skin, and resulted in faster resolution of pain and tenderness.
The Herpesviridae family (Types 1-8) continues to inflict considerable morbidity and social stigma upon humanity. Once infected with the herpes viruses, especially Types 1-3, they establish permanent residence within our nervous system and reactivate during periods of stress, trauma, and/or other precipitating factors.
Genital herpes simplex and herpes zoster infections are common afflictions that are associated with significant morbidity and a decreased quality of life. Famciclovir (Famvir®, Novartis) is an orally administered prodrug of the antiviral agent penciclovir.
Penciclovir cream (Vectavir™/Denavir™, SmithKline Beecham) is a novel product, approved in 15 countries including the USA and UK, for the treatment of herpes simplex labialis in immunocompetent adults.