MICROBIOLOGY AND CLINICAL MICROBIOLOGY
Learning outcomes of the course unit
Acquisition of the scientific expertise instrumental to the understanding of the taxonomic, epidemiological, morphological, physiological, immunological and pharmacological characteristics of bacteria, fungi, parasites and viruses responsible for infectious diseases in man and capacity of evaluation, interpretation and managing of microbiological and virological approaches for the diagnosis, therapy, prophylaxis and control of the infections of the oral cavity and cross-infections in dentistry.
Course contents summary
Evolution of microorganisms and microbiology. The bacteria: cell structure, classification, reproduction, sporogenesis and germination, metabolism, cultivation, genetics, mechanisms of pathogenicity. The fungi: yeasts, moulds. The parasites: protozoa, metazoa. The viruses: chemical composition and structure, classification, replication, interference, cultivation and quantitation, mechanisms of pathogenicity. General outlines on infectious diseases: endogenous infections, exogenous infections. Innate and adaptative immunity against infections. Principles of direct and indirect microbiological diagnosis. Antibacterial drugs. Antifungal drugs. Antiparasitic drugs. Antiviral drugs. Mechanisms of resistance of pathogenic agents to anti-infective drugs. Principles of drug sensitivity testing of pathogenic agents to anti-infective drugs. Prevention of infectious diseases: active immunity, passive immunity. The mouth as a microbial habitat. The resident oral microbial population. Acquisition, adhesion, distribution and metabolism of the oral microbial population. Dental plaque. Dental caries. Periodontal diseases. Oral bacterial infections. Oral fungal infections. Oral viral infections. Therapy and prophylaxis of oral infections. Cross-infection control in dentistry. Microbiological principles for disinfection and sterilization.
M. Bendinelli, C. Chezzi, G. Dettori, N. Manca, G. Morace, L. Polonelli, M.A. Tufano. Microbiologia Medica. Gli agenti infettivi dell'uomo: biologia, azione patogena, laboratorio. Batteriologia. Micologia. Virologia. Monduzzi Editore.
L. Polonelli. Microbiologia Odontoiatrica. UniNova. Traduzione da P. Marsh, M.V. Martin. Oral Microbiology. Wright.