DearCustomerbr /> I have been asked to answer this question. In general the term implies enlargement of a particular organ or part or structure due to degeneration of that particular part. In musculoskeletal system margins of joints form osteophyte which are outgrowths of bones at margins of joints. These are usually formed in response to degenerative changes and these are examples of hypertrophic degeneration. Please ask if you have any more queries.