Vitamin B12 deficiency: Feeling this sensation in the chest could mean pernicious anaemia
VITAMIN B12 is one of the main "raw materials" needed to build the healthy red blood cell; the other is folate or folic acid. In order to make healthy red blood cells that can carry oxygen around the body a person needs adequate levels of B12. Feeling this sensation in your chest is a warning sign of pernicious anaemia.
This study assessed whether GPCA-positive BMS (GPCA+BMS) patients had significantly higher frequencies of macrocytosis, anemia, hematinic deficiencies, and hyperhomocysteinemia than healthy control subjects or GPCA-negative BMS (GPCA-BMS) patients. METHODS: The mean corpuscular volume, blood hemoglobin (Hb), and serum iron, vitamin B12, folic acid, homocysteine, and GPCA levels were measured and compared between any two of three groups of 109 GPCA+BMS patients, 775 GPCA-BMS patients, and 442 healthy control subjects. RESULTS: We found that 109 GPCA+BMS patients had significantly higher frequencies of macrocytosis...
Vitamin B12 is essential for the formation of red blood cells in the bone marrow. Its deficiency is mainly caused by gastrointestinal malabsorption and can result in pernicious anemia. Some oral signs and symptoms, such as burning sensation, glossitis with papillary atrophy, and areas of painful erythema, can be associated. Here, we report 3 cases of oral manifestations associated with vitamin B12 deficiency. The first patient was a 36-year-old male, and the other 2 were females, 61 and 70 years old.
Vitamin B12 (B12), also known as cobalamin, is a water-soluble vitamin. It is a cofactor in DNA synthesis and is involved in the metabolism of every cell of the human body, including the central nervous system. Those with a deficiency of B12 can present with peripheral neuropathy, pernicious anemia, or a cognitive disorder. Previous studies have revealed that a deficiency of B12 is associated with cognitive decline or Alzheimer disease. The data of 2991 people were evaluated from 2 years of the Korean Frailty and Aging Cohort Study, a nationwide multicenter survey. To assess cognitive function, a short form of the Korean ...
We report a 48-year-old gentleman who presented with a 1-week history of dizziness and upper gastrointestinal bleeding. Laboratory evaluation revealed pancytopenia, macrocytosis, toxic neutrophils, hemolysis, suppressed reticulocyte count, positive direct anti-globulin test (DAT), severely reduced B12 levels, and positive anti-intrinsic factor and anti-parietal cell antibodies. He was started on weekly intramuscular B12 supplementation and showed improvement in blood cell counts during follow-up. Recognition of B12 deficiency as a cause of pancytopenia and DAT-positive autoimmune hemolytic anemia can help to avoid unwanted...
VITAMIN B12 deficiency produces a number of eerie effects on the body and the type of symptoms you may experience depend on the underlying cause. One common warning sign associated with B12 deficiency caused by pernicious anaemia is a particular sound.
VITAMIN B12 aids the body in essential ways yet some people struggle to absorb the vitamin due to an underlying condition called pernicious anaemia. This can raise one's risk of developing B12 deficiency - here are five early warning signs.
VITAMIN B12 deficiency is mainly caused by a condition called pernicious anaemia. The autoimmune condition prevents the body from benefiting from the nutrient. And a sign in your vision could indicate you're having trouble absorbing it.
VITAMIN B12 deficiency is primarily caused by an autoimmune condition called pernicious anaemia. One sign of B12 deficiency caused by pernicious anaemia can be spotted in the shower.
VITAMIN B12 supports the body's vital functions yet some people struggle to get enough of the vitamin because of an underlying condition called pernicious anaemia. One sign of a B12 deficiency caused by pernicious anaemia can be spotted when you wake up in the morning.
VITAMIN B12 deficiency can lead to a health condition called pernicious anemia. What exactly is it? What are the symptoms? And who is at risk?