Our onboard computer, the brain, is a sterile environment separated from the immune system by the blood-brain barrier (BBB), which is why it has its own resident immune cells, known … Continue Reading New role for white blood cells in the developing brain.
An ever-growing epidemic, obesity is a chronic medical condition where excess body fat has accumulated to the point it may cause a multitude of health disorders. Several studies have also … Continue Reading Visceral fat delivers a signal to the brain that impairs cognition.
Autism spectrum disorders (ASD) affect around 1% of the world’s population and are characterized by a range of difficulties in social interaction and communication. There are many different genetic mutations … Continue Reading Researchers identify a new form of autism.
Hypertension is a leading risk factor for dementia, however, the mechanisms underlying its damaging effects on the brain are poorly understood. Now, a study from researchers at Weill Cornell Medicine … Continue Reading Immune cells identified as the culprit linking hypertension and dementia.
Adult brain cancers are almost always universally fatal, due in part to the biochemical composition of the central nervous system and the blood-brain barrier, which selectively and protectively limits the … Continue Reading Animal study shows depriving deadly brain cancer of cholesterol kills tumour cells.
Alzheimer’s disease is characterized by the degeneration of neurons in the hippocampus and cortex, and the appearance of neuritic plaques and neurofibrillary tangles. Although the precise cause of Alzheimer’s disease remains … Continue Reading Researchers elevate brain protein to allay symptoms of Alzheimer’s in animal model.
The rapid rise in obesity and associated spread of type 2 diabetes represent an enormous challenge for society, with no efficient and safe medicines to prevent or stop this development … Continue Reading Astrocytes shown to control sugar in the brain, as well as neurons.
Delayed deterioration of neurological function after ischemia stroke is a well-documented clinical problem. However, minimal studies exist pertaining to spinal cord blood flow and blood-spinal cord barrier (BSCB) integrity with … Continue Reading Study maps how a stroke damages the blood-spinal cord barrier.
The blood-brain barrier (BBB), a collection of cells and subcellular structures in the cerebrovascular wall that separates the circulating blood from the brain, is essential to keep brain tissue in … Continue Reading Leakages identified in the blood-brain barrier of patients with early Alzheimer’s disease.
The intestines’ primary role is digestion, however, they must also achieve high performance around the clock defending against pathogens and environmental pollutants. This is because everything taken up with food … Continue Reading Study shows how an important intestinal immune response controller works.
Presently, there are limitations to drug delivery to the brain as it is tightly protected by the blood-brain barrier. The blood-brain barrier is a protective barrier which separates the circulating … Continue Reading Researchers derive first ever molecular model of critical blood-brain barrier transporter.
When the blood-brain barrier (BBB) is breached the brain becomes vulnerable to infection and injury. Therefore, it’s imperative that the openings in the BBB are resealed quickly. This most frequently … Continue Reading Researchers identify new role for microglia in blood-brain barrier maintainence.
The blood-brain barrier represents a fundamental limitation in treating neurological disease because it prevents all neuropeptides from reaching the central nervous system (CNS). Currently, there is no efficient method to … Continue Reading New technique bypasses the blood-brain barrier to deliver neuroprotection.
In Alzheimer’s, the brain begins to change years before symptoms emerge. Detecting Alzheimer’s antibodies at the preclinical stage would give patients an opportunity to work with their physician to make … Continue Reading Researchers nearing a blood test for Alzheimer’s disease.
Neural stem cells generate new neurons throughout life in the mammalian brain. Neural stem cells are self-renewing, multipotent cells that generate the main phenotype of the nervous system. Stem cells … Continue Reading Researchers identify neuroprotective mechanism against stem cell aging.
Alzheimer’s is the most common form of dementia globally and affects up to 40,000 people in Ireland today. It is the fourth leading cause of death in individuals over the … Continue Reading Researchers have discovered clearance of Alzheimer’s protein across the blood-brain barrier.