Shotgun sequencing and dealing with repeat sections.
15477. The public Human Genome Project: mapping the genome, sequencing, and reassembly. 3D animation.
The public Human Genome Project: mapping the genome, sequencing, and reassembly.
Eric Lander talks about whole genome shotgun.
Problems using shotgun method on Drosophila.
Nobel Laureate John Sulston, a key figure in the UK sequencing effort, talks about breaking DNA apart so that the sequence can be reassembled.
Eric Lander talks about analysis in public and private Human Genome Projects.
Craig Venter, the leader of the private genome effort, talks about the "whole genome shotgun" technique that was used by Celera Genomics to sequence the human genome.
James Watson describes sequencing the human genome using markers and BACs, and Craig Venter explains using cDNA libraries, ESTs, and shotgun sequencing.
John Sulston, a key figure in the public genome project, speaks about the difficulties posed by missing a step in the sequencing process.