About Systemic Sclerosis
Systemic disease is an auto immune disease which affects the systemic connective tissues. Systemic sclerosis is characterised by vasomotor disturbances, fibrosis, subsequent atrophy of the skin, subcutaneous tissue, muscles, and internal organs (e.g., alimentary tract, lungs, heart, kidney, CNS) and immunologic disturbances. There are two types of systemic sclerosis localized and systemic scleroderma. Localized scleroderma affects only skin and systemic affects kidneys, heart, lungs, and gastrointestinal tract.