As the momentum builds in Aicardi syndrome research we will continue to outline the progress. Thank you to Baylor College of Medicine and the University of California San Francisco for what we know today.
At Baylor College of Medicine scientists have been looking for genetic changes that may be the cause of Aicardi Syndrome using a new method, microarray-based comparative genomic hybridization (array-CGH). This technique involves a DNA chip, the size of a microscope slide, with hundreds of thousands of small pieces of DNA attached to it.
Dr. Elliott Sherr and his collaborators at University of California, San Francisco (UCSF) are studying the genetic causes of disorders of cognition and epilepsy, in particular disorders of brain development that affect the corpus callosum, such as Aicardi syndrome, as well as two additional brain malformations, polymicrogyria and Dandy-Walker malformation.