No matter how much you might like grandfather's bald head, most men are unhappy about balding. That is why millions of dollars are spent every year trying to stop it from happening. The cure may finally be on the way.
Researchers at Rockefeller University research used stem cells from adult skin to grow hair. Small amounts of stem cells were discovered saved in each hair follicle to replace skins cells when they die. One stem cell could grow hair, skin and oil glands. Scientists attached grafted them, skin and all, to the body (in this case a test mouse). The hair grew and the new skin had oil glands keeping it healthy and best of all, the bald spot was gone!
(Sender, Aaron J. "Bald Men: This Mouse Is for You." Discover January 2005: p. 33)
1. Can using stem cells to graft hair to the scalp cure baldness?
Disciplinary Core Ideas
LS1.A: Structure and Function: LINK
• Systems of specialized cells within organisms help them perform the essential functions of life. (HS-LS1-1)
• All cells contain genetic information in the form of DNA molecules. Genes are regions in the DNA that contain the instructions that code for the formation of proteins, which carry out most of the work of cells. (HS-LS1-1) (Note: This Disciplinary Core Idea is also addressed by HS-LS3-1.)
• Multicellular organisms have a hierarchical structural organization, in which any one system is made up of numerous parts and is itself a component of the next level. (HS-LS1-2)
• Feedback mechanisms maintain a living system’s internal conditions within certain limits and mediate behaviors, allowing it to remain alive and functional even as external conditions change within some range. Feedback mechanisms can encourage (through positive feedback) or discourage (negative feedback) what is going on inside the living system. (HS-LS1-3
Science and Engineering Practices
Developing and Using Models
• Develop and use a model based on evidence to illustrate the relationships between systems or between components of a system. (HS-LS1-2)
• Use a model based on evidence to illustrate the relationships between systems or between components of a system. (HS-LS1-4),(HS-LS1-5),(HS-LS1-7)
Planning and Carrying Out Investigations
• Plan and conduct an investigation individually and collaboratively to produce data to serve as the basis for evidence, and in the design: decide on types, how much, and accuracy of data needed to produce reliable measurements and consider limitations on the precision of the data (e.g., number of trials, cost, risk, time), and refine the design accordingly. (HS-LS1-3)
Constructing Explanations and Designing Solutions
• Construct an explanation based on valid and reliable evidence obtained from a variety of sources (including students’ own investigations, models, theories, simulations, peer review) and the assumption that theories and laws that describe the natural world operate today as they did in the past and will continue to do so in the future. (HS-LS1-1)
• Construct and revise an explanation based on valid and reliable evidence obtained from a variety of sources (including students’ own investigations, models, theories, simulations, peer review) and the assumption that theories and laws that describe the natural world operate today as they did in the past and will continue to do so in the future. (HS-LS1-6)
Systems and System Models
• Models (e.g., physical, mathematical, computer models) can be used to simulate systems and interactions—including energy, matter, and information flows—within and between systems at different scales. (HS-LS1-2),(HS-LS1-4)
Energy and Matter
• Changes of energy and matter in a system can be described in terms of energy and matter flows into, out of, and within that system. (HS-LS1-5), (HS-LS1-6)
• Energy cannot be created or destroyed—it only moves between one place and another place, between objects and/or fields, or between systems. (HS-LS1-7) )
Structure and Function
• Investigating or designing new systems or structures requires a detailed examination of the properties of different materials, the structures of different components, and connections of components to reveal its function and/or solve a problem. (HS-LS1-1)
Connections to Nature of Science
Scientific Investigations Use a Variety of Methods
• Science knowledge is based upon logical connections between evidence and explanations. (MS-LS1-6)
Other questions that were generated in researching this Scientific Phenomena?
Using Discoveries and Inventions as Scientific Phenomena to Integrate with NGSS:
Scientific Phenomena can be used as a tool to anchor a science unit involving a series of lessons to engage in deeper science learning – or what is being called “Three Dimensional Learning”.
1) Describe the phenomena in a way that your students can understand and which sparks their imagination.
2) Create Essential Questions for them to answer to explain the phenomena.
3) Identify the NGSS Disciplinary Core Ideas which you are targeting.
4) Provide clear directions for a process they should use to try to answer the questions using the NGSS Science and Engineering Practices to frame as your guideline.
5) Name the Crosscutting Concepts that students should be aware of throughout the lesson.
6) Discuss the Connections to Nature of Science.
7) Make note of other questions generated in the process of exploring this Scientific Phenomena.