Join Britannica's Publishing Partner Program and our community of experts to gain a global audience for your work! Chloroquine, introduced into medicine in the 1940s, is a member of an important series of chemically related antimalarial agents, the quinoline derivatives. Chloroquine is administered orally as chloroquine phosphate. Color vision changes associated with plaquenil toxicity Chloroquine effets secondaires Hydroxy chloroquine resistant malaria Hydroxychloroquine dose by weight Chloroquine acts by diffusing into the red blood cells, the parasite, and the vacuole. It becomes trapped in the vacuole, and reacts with the heme crystals. In this form, the crystals cannot have any more heme molecules added. Chloroquine phosphate comes as a tablet to take by mouth. For prevention of malaria in adults, one dose is usually taken once a week on exactly the same day of the week. Your doctor will tell you how many tablets to take for each dose. One dose is taken beginning 2 weeks before traveling to an area. Apr 02, 2019 Chloroquine resistance is widespread and, at present, is particularly prominent in various parts of the world including sub- Saharan Africa, Southeast Asia, the Indian subcontinent, and over large portions of South America, including the Amazon basin 1. Chloroquine is effective against susceptible strains of the malarial parasites , as well as certain parasitic worms and amoebas. It also can be given by intramuscular injection as chloroquine hydrochloride. What is in chloroquine Claim that chloroquine can prevent coronavirus a scam — Prof., Chloroquine MedlinePlus Drug Information How long does it take plaquenil to workHydroxychloroquine sulfate tabsHow often do you take plaquenilChloroquine usmleCan you take omeprazole with plaquenil Chloroquine also known as chloroquine phosphate is an antimalarial medicine. It is available in the. United States by prescription only. It is sold under the brand name Aralen, and it is also sold as a generic medicine. It is available in tablets of two sizes 150mg base 250mg salt and 300mg base 500mg salt. Medicines for the Prevention of Malaria While Traveling - Chloroquine.. Aralen Chloroquine Uses, Dosage, Side Effects.. What Is the Difference between Hydroxychloroquine and Chloroquine?. Medical Definition of chloroquine. an antimalarial drug administered in the form of its diphosphate C 18H 26ClN 3 2H 3PO 4 or hydrochloride C 18H 26ClN 3 HCl. Chloroquine Phosphate. Chloroquine is used to prevent or treat malaria caused by mosquito bites in countries where malaria is common. Malaria parasites can enter the body through these mosquito bites, and then live in body tissues such as red blood cells or the liver. Chloroquine binds to plasma proteins that are deposited in tissues, such as the liver, spleen, kidney, and lung. Chloroquine has a particularly high affinity for melanin-containing cells and hence there are very high levels of chloroquine in the skin mainly, the epidermis and retina.