* A number of important concepts are discussed, including:
* How polarity is established during oogenesis
* How germ cell determinants become organized in the establishment of the germ cell lineage
* Different strategies used by organisms to establish the germ cell lineage
* Similarities and differences between the mechanisms used in embryonic patterning
* The mechanisms and machinery by which molecules such as RNA become asymmetrically segregated
* The use of similar signaling pathways in patterning of the dorsal-ventral and right-left asymmetries, embryonic germ layers, limb, and nervous system
* The link between fundamental biological processes such as RNA translation and localization in the regulation of axis specification
International Review of Cytology presents current advances and comprehensive reviews in cell biology, both plant and animal. Articles address structure and control of gene expression, nucleocytoplasmic interactions, control of cell development and differentiation, and cell transformation and growth. Authored by some of the foremost scientists in the field, each volume provides up-to-date information and directions for future research.
This volume brings together current information on the localization and roles of RNAs in cell-lineage determination and subsequent patterning in embryonic development. Guest co-editor Lawrence Etkin is one of the leading researchers in molecular genetics of Xenopus.
Cell biologists, molecular biologists, developmental biologists, physiologists (organ level), biomedical scientists, biochemists studying cell-cell interactions, cell variation, and evolution.
Cell Lineage and Embryo Patterning, 1st Edition
Specification of the Cell Lineages:
Determinants of Cell and Positional Fate in Ascidian Embryos, W.R. Jeffery
RNA Localization and Germ Cell Determination in Xenopus, M. Kloc, S. Bilinski, A. P-Y. Chan, L.H. Allen, N.R. Zearfoss, and L.D. Etkin
Asymmetric Germ Cell Division and Oocyte Determination during Drosophila
Oogenesis, W. Deng and H. Lin
The Germline in C. elegans
: Origins, Proliferation, and Silencing, G. Seydoux and T. Schedl
Assembly of the Drosophila
Germ Plasm, A.P. Mahowald
Early Events in Mammalian Germ Line, R. Anderson, J. Heasman, and C. Wylie
.Patterning of the Embryo:
The Initial Phase of Embryonic Patterning in Mammals, R.L. Gardner
Cadherin and Catenins, Wnts and Soxs: Embryonic Patterning in Xenopus, A.L. St. Amand and M.W. Klymkowsky
Establishment of Left-Right Asymmetry, H.J. Yost
Initiation and Early Patterning of the Endoderm, D. Clements, M. Rex, and H.R. Woodland
Neural Patterning in the Vertebrate Embryo, C.R. Altmann and A. Hemmati-Brivanlou
Cell Biology of Limb Patterning, S.A. Schaller, S. Li, V. Ngo-Muller, M.-J. Han, M. Omi, R. Anderson, and K. Muneoka
.Mechanisms to Establish Polarity and Initiate Cell Fate Determination:
Defining Cis-Acting Elements and Trans-Acting Factors in RNA Localization, K. Yaniv and J.K. Yisraeli
RNA Localization and Translational Regulation during Axis Specification in the Drosophila
Oocyte, R.L. Cooperstock and H.D. Lipshitz
Translational Control in Vertebrate Development, C.H. de Moor and J.D. Richter
Quotes and reviews
@from:Praise for the Series
@qu:"Invaluable reading for all biologists."
@qu:"In keeping with the high standards set by the editors... carefully prepared and edited in the customary fine format and well-illustrated style of Academic Press publications... this series is a significant contribution to a science that impinges on many fields."
@source:--THE QUARTERLY REVIEW OF BIOLOGY
@qu:"A valuable addition to any college library as current reference material for advanced undergraduates, graduate students, and professional scientists."
@qu:"Maintains the tradition and set-up of the previous volumes and certainly provides up-to-date data on varied aspects of cytology... a valuable acquisition to any library."
@qu:"Should be on the shelf of any biomedical library."
@source:--Alvin Tesler, Northwestern Medical School, in DOODY'S