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Sep 17

CT-ΔBench: A Benchmark for Longitudinal 3D Medical Imaging Difference Reporting with Vision-Language Models

In medical imaging, the clinical value of Computed Tomography (CT) lies not only in depicting current disease status, but crucially in enabling longitudinal comparison of serial scans to determine disease evolution, a process that underpins response assessment, recurrence detection, and ongoing patient management. Yet, despite this central role of temporal comparison in clinical decision-making, existing medical foundation models remain largely confined to single-study understanding, leaving temporally grounded cross-examination insufficiently addressed. To address this gap, we study longitudinal imaging difference reporting, a task in which a model takes two temporally separated scans from the same patient and generates a clinically meaningful report describing interval changes between them. We introduce CT-ΔBench, a dedicated benchmark for this task with patient-level splitting to prevent information leakage. To better evaluate this task beyond surface-level text similarity, we further develop change-aware metrics specifically designed to capture clinically meaningful longitudinal changes, and conduct an independent physician validation to assess the reliability of the synthesized references and event extraction pipeline. We also compare direct paired-CT reasoning with an indirect two-stage pipeline that first generates single-timepoint reports and then performs textual differencing. Finally, we propose DeltaMed, a baseline model for direct paired-CT difference reporting, and train it on the benchmark training set. Together, these contributions lay the groundwork for temporally aware medical foundation models that better reflect real-world longitudinal clinical reasoning.

  • 4 authors
·
Aug 11

Learning Stratigraphically Consistent Relative Geologic Time from 3D Seismic Data via Sinusoidal Mapping

Relative Geologic Time (RGT) estimation from seismic data is a cornerstone of subsurface structural modeling, depositional evolution analysis, and reservoir characterization, supporting horizon correlation and depositional system reconstruction. Yet accurate RGT estimation remains challenging: RGT is intrinsically a topologically constrained continuous field, in which local errors readily propagate globally and distort the overall result. Conventional methods rely heavily on priors, attribute extraction, and manual interaction, leading to cumbersome workflows. Existing deep-learning approaches mostly use a regression formulation with pixel-wise MSE/MAE losses, which struggle to capture thin horizons and fail to model the stratigraphic semantics of the RGT field, yielding limited generalization and unstable ordering across diverse structural and depositional settings. We propose RGT-Est, a deep-learning framework that transfers the optimization target from the topologically constrained continuous field into a differentiable sinusoidal space, which explicitly encodes the periodic stratigraphic semantics of RGT and alleviates over-smoothing of fine horizons. Pointwise, perceptual, and adversarial losses are jointly imposed in this space to enforce local fidelity, inter-layer consistency, and global structural plausibility, providing both fine-horizon discrimination and global stratigraphic awareness. An optional horizon-guidance module further accepts sparse 2D or 3D horizons as priors. Trained on synthetic data and evaluated on field surveys with densely faulted zones, large unconformities, steeply dipping strata, folded deformations, and clinoforms, RGT-Est achieves state-of-the-art performance among AI-based methods without horizon constraints, and attains substantially higher horizon-correlation accuracy and global topological consistency once sparse priors are incorporated.

  • 4 authors
·
May 10

DiffPose: SpatioTemporal Diffusion Model for Video-Based Human Pose Estimation

Denoising diffusion probabilistic models that were initially proposed for realistic image generation have recently shown success in various perception tasks (e.g., object detection and image segmentation) and are increasingly gaining attention in computer vision. However, extending such models to multi-frame human pose estimation is non-trivial due to the presence of the additional temporal dimension in videos. More importantly, learning representations that focus on keypoint regions is crucial for accurate localization of human joints. Nevertheless, the adaptation of the diffusion-based methods remains unclear on how to achieve such objective. In this paper, we present DiffPose, a novel diffusion architecture that formulates video-based human pose estimation as a conditional heatmap generation problem. First, to better leverage temporal information, we propose SpatioTemporal Representation Learner which aggregates visual evidences across frames and uses the resulting features in each denoising step as a condition. In addition, we present a mechanism called Lookup-based MultiScale Feature Interaction that determines the correlations between local joints and global contexts across multiple scales. This mechanism generates delicate representations that focus on keypoint regions. Altogether, by extending diffusion models, we show two unique characteristics from DiffPose on pose estimation task: (i) the ability to combine multiple sets of pose estimates to improve prediction accuracy, particularly for challenging joints, and (ii) the ability to adjust the number of iterative steps for feature refinement without retraining the model. DiffPose sets new state-of-the-art results on three benchmarks: PoseTrack2017, PoseTrack2018, and PoseTrack21.

  • 5 authors
·
Jul 31, 2023

Where Pretraining writes and Alignment reads: the asymmetry of Transformer weight space

Cross-entropy pretraining and preference alignment update the same transformer weights, but leave geometrically distinct traces. We characterise this asymmetry with a relative-subspace-fraction probe that tracks how weight deltas align with residual-stream activation subspaces and with the prediction subspace defined by the unembedding. Alignment deltas concentrate in the read pathway (W_Q, W_K), along principal directions of attention-input activations, while remaining near-isotropic in the write pathway (W_O, W_2) relative to the prediction subspace. We explain this pattern through anisotropic gradient accumulation: updates to a matrix W are sums of outer products δ_t a_t^top, and inherit directional structure from whichever side has concentrated covariance. For read-pathway matrices, this side is the input activation a_t, whose covariance is spiked in trained transformers and therefore produces objective-agnostic concentration. For write-pathway matrices, the relevant side is the upstream gradient δ_t, whose anisotropy depends on the loss. Cross-entropy supplies the canonical sharp per-sample signal, inducing write-pathway prediction geometry during pretraining; alignment objectives typically add little further write-side concentration. We support this explanation with a within-checkpoint trajectory, a graded contrastive-objective control, and a closed-form rank-1 intervention with matched direction controls, providing causal evidence for the proposed weight-space geometry.

  • 3 authors
·
May 14